Chemical Name: 3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-1,5,11alpha,14,19-pentahydoxycard-20(22)-enolide octahydrate. Alternate Names: G-strophanthin, Strophanthin G
Na+ K+ ATPase inhibitor
Molecular Weight:
584.67 144.12
Purity:
99% by TLC, NMR (conforms)
Form:
White solid
CAS Number:
[11018-89-6]
Formula:
C29H44O12 8(H2O)
Application Notes:
Selective inhibitor of Na+ K+-ATPase isolated from Strophanthus gratus1. Endogenous ouabain is found in human circulation2. Displays cardiotonic and diuretic activity. May be used to induce hypertensive rat model3. Cell permeable and active in vivo.
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