Chemical Name: 1-(beta-D-Ribofuranosyl)-5-fluorouracil. Alternate Names: FUrd
Proapoptotic antiproliferative agent
Molecular Weight:
262.19
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[316-46-1]
Formula:
C9H11FN2O6
Application Notes:
Inhibitor of ribozyme self-cleavage in mammalian cells.1 Induces apoptosis in HCT-116 colorectal carcinoma cells causing diverse gene expression patterns suggesting that mechanisms besides global inhibition of RNA synthesis and processing contribute to 5-fluorouridine cytotoxicity.2 Cell permeable and active in vivo.
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