Chemical Name: (E)-3-(4-Methylphenylsulfonyl)-2-propenenitrile
IKK inhibitor
Molecular Weight:
207.27
Purity:
98% by TLC
Form:
Off-white solid
CAS Number:
[19542-67-7]
Formula:
C10H9NO2S
Application Notes:
BAY 11-7082 selectively inhibits TNF-induced phosphorylation of kappa-alpha leading to decreased nuclear NF-kappaB and decreased adhesion molecule expression without affecting constitutive kappa-alpha phosphorylation.1 The effects on adhesion molecule expression were found to be irreversible.
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