Chemical Name: 3-(N,N-Dimethylsulfonamido)-4-methylnitrobenzene
PDE7 inhibitor
Molecular Weight:
244.27
Purity:
98% by TLC, NMR (Conforms)
Form:
Off-white solid
CAS Number:
[433695-36-4]
Formula:
C9H12N2O4
Application Notes:
Potent and selective inhibitor of phosphodiesterase-7 (PDE7), Ki=180 nM1. Induces apoptosis in chronic lymphocytic leukemia cells which express PDE7B2. Increases mineralization in osteoblasts differentiated from hMSC3. Cell permeable.
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