Chemical Name: Cyclohexylcarbamic acid 3-(aminocarbonyl)-[1,1-biphenyl]-3-yl ester
FAAH inhibitor
Molecular Weight:
338.41
Purity:
98% by TLC, NMR (Conforms)
Form:
Off-white solid
CAS Number:
[546141-08-6]
Formula:
C20H22N2O3
Application Notes:
Potent and selective fatty acid amide hydrolase (FAAH) inhibitor, IC50 = 3-5 nM1. Produces cannabinoid CB1 and CB2 receptor-mediated analgesia in inflammatory pain states without causing side effects associated with cannabinoid receptor activation2. Attenuates the anxiolytic-like effect of acetaminophen in a mouse model3. Exerts anti-inflammatory effects in rat hippocampus and ameliorates age-related deficits4. Off target effects: Reduces tyrosine hydroxylase expression5.
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