LDN-57444, CAS [[668467-91-2]]

Product Overview

• Article Name: LDN-57444, CAS [[668467-91-2]]
• Biozol Catalog Number: FBM-10-1303
• Supplier Catalog Number: 10-1303
• Alternative Catalog Number: FBM-10-1303-5MG, FBM-10-1303-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-acetyloxime)

Product Description

DUB inhibitor

Product Properties

• Molecular Weight: 397.65
• Purity: 98% by TLC, NMR conforms
• Form: Yellow solid
• CAS Number: [668467-91-2]
• Formula: C17H11Cl3N2O3

Application Notes

• Application Notes: Inhibits ubiquitin C-terminal hydrolase (UCH-L1) (Ki=0.4 M). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis. Causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. Cell permeable.