C-646, CAS [[328968-36-1]]

Catalog Number: FBM-10-1306
Article Name: C-646, CAS [[328968-36-1]]
Biozol Catalog Number: FBM-10-1306
Supplier Catalog Number: 10-1306
Alternative Catalog Number: FBM-10-1306-5MG, FBM-10-1306-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: 4-[4-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl]benzoic acid
HAT inhibitor
Molecular Weight: 445.44
Purity: 98% by TLC, NMR conforms
Form: Orange solid
CAS Number: [328968-36-1]
Formula: C24H19N3O6
Application Notes: Potent and selective inhibitor of the histone acetyl transferase p300/CBP (Ki=400 nM ). Induces apoptosis in prostate cancer cells. Enhances fear extinction memory and synaptic plasticity in mice. Promotes tau deacetylation reducing levels of pathogenic p-tau. Cell permeable.