Glyburide, CAS [[10238-21-8]]

Product Overview

• Article Name: Glyburide, CAS [[10238-21-8]]
• Biozol Catalog Number: FBM-10-1325
• Supplier Catalog Number: 10-1325
• Alternative Catalog Number: FBM-10-1325-1G, FBM-10-1325-5G
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]suphonyl]phenyl]ethyl]-2-methoxybenzamide. Alternate Names: Glibenclamide

Product Description

K-ATP channel blocker

Product Properties

• Molecular Weight: 494.01
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [10238-21-8]
• Formula: C23H28ClN3O5S

Application Notes

• Application Notes: Second generation oral hypoglycemic agent. Acts via ATP-dependent K+ channel (Kir6, KATP) block1. Inhibits Kir6 currents in the pancreas, causing an increase in intracellular Ca2+ and insulin secretion. Also inhibits recombinant CFTR Cl- channels with an IC50 of 20 µM2. Cell permeable.