Chemical Name: 2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol
p53/mdm2 inhibitor
Molecular Weight:
340.43
Purity:
97% by TLC / HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[6964-62-1]
Formula:
C23H20N2O
Application Notes:
A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable.
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