Chemical Name: 2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]-N-(1-phenylethyl)benzamide
SIRT inhibitor
Molecular Weight:
394.48
Purity:
>98% by TLC, NMR (Conforms)
Form:
Pale yellow solid
CAS Number:
[410536-97-9]
Formula:
C26H22N2O2
Application Notes:
Inhibitor of sirtuin family enzymes including human SIRT1 (IC50=60µM), human SIRT2 (IC50=58µM), and yeast Sir2 (IC50=48µM) with no inhibition of human HDAC1. Active in vivo and in purified enzyme studies. Cell permeable.
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