Chemical Name: N-[(2R)-2-(Hydroxamidocarbonylmethyl)-4-methylpentanoyl]-L-tryptophan methylamide. Alternate Names: GM-6001
MMP inhibitor
Molecular Weight:
388.46
Purity:
97% by TLC
Form:
White solid
CAS Number:
[142880-36-2]
Formula:
C20H28N4O4
Application Notes:
Potent pan-specific inhibitor of matrix metalloproteinases (MMPs).1 Ki values have been reported for the following human MMPs: MMP-1, 0.4nM, MMP-2, 0.5nM, MMP-3, 27nM, MMP-7, 3.7nM, MMP-8, 0.1nM, MMP-9, 0.2nM, MMP-12, 3.6nM, MMP-14, 13.4nM, MMP-26, 0.36nM.2-4 Also inhibits MMP-10, MMP-13, MMP-15, MMP-17, MMP-20, MMP-21, TACE and ADAM19.
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