Chemical Name: 2-Ethyl-2-(imidazolin-2-yl)-2,3-dihydrobenzofuran, hydrochloride. Alternate Names: RX 821037A
alpha2 adrenergic antagonist
Molecular Weight:
252.74
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[89197-00-2]
Formula:
C13H16N2O HCl
Application Notes:
Selective alpha2-adrenergic receptor antagonist1 (selectivity ratio of alpha2/alpha1 = 724)4 and imidazoline receptor antagonist2. Induces release of insulin in the rat insulinoma cell line RIN-5AH by interaction with ATP-sensitive potassium channels independently from imidazoline I1 or I2 receptors.3 Increases resting plasma insulin levels and markedly potentiates the rise in insulin levels produced by adrenaline in the rat.4
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