Chemical Name: N-Acetyl-Leu-Leu-Methional. Alternate Names: Ac-LLM-CHO, Calpain inhibitor II
Calpain inhibitor
Molecular Weight:
401.56
Purity:
98% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[136632-32-1]
Formula:
C19H35N3O4S
Application Notes:
Cell-permeable, peptide aldehyde inhibitor of calpain (calpain I, Ki = 120 nM, calpain II, Ki = 230 nM) and other neutral cysteine proteases. Potent inhibitor of cathepsin L (Ki=0.6 nM) and cathepsin B (Ki=100 nM).1 Weak inhibitor of the chymotrypsin-like activity of the proteasome.2 Cell permeable.
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