Chemical Name: ()-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one
p53/mdm2 inhibitor
Molecular Weight:
581.51
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[548472-68-0]
Formula:
C30H30Cl2N4O4
Application Notes:
MDM2 antagonist, inhibits the MDM2-p53 interaction (IC50 = 0.09 µM) and activates p531. Displays antiproliferative activity and induces apoptosis in a variety of tumor cells2-4.
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