Chemical Name: N-(3-Methylphenyl)-4-(4-pyridinyl)-2-thiazolamine
Autophagy inducer
Molecular Weight:
477.41
Purity:
98% by TLC, NMR (conforms)
Form:
Off-white solid
CAS Number:
[315702-99-9]
Formula:
C15H13N3S
Application Notes:
Specifically induces autophagic cell death in VHL (von Hippel-Lindau)-deficient renal carcinoma cells both in vitro (IC50=625 nM) and in vivo. Renal cell carcinoma cell lines were radiosensitized by induction of autophagy following treatment with STF-62247. Cell permeable
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