Hydroxychloroquine sulfate, CAS [[747-36-4]]

Product Overview

• Article Name: Hydroxychloroquine sulfate, CAS [[747-36-4]]
• Biozol Catalog Number: FBM-10-1379
• Supplier Catalog Number: 10-1379
• Alternative Catalog Number: FBM-10-1379-50MG, FBM-10-1379-250MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 7-Chloro-4-[4-(N-ethyl-N-b-hydroxyethylamino)-1-methylbutylamino]quinolone sulfate

Product Description

Autophagy inhibitor

Product Properties

• Molecular Weight: 433.96
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [747-36-4]
• Formula: C18H26ClN3O H2SO4

Application Notes

• Application Notes: Hydroxychloroquine sulfate is a lysosomotropic agent which inhibits autophagy and triggers apoptosis in a variety of cell types.1,2 Augments the anticancer activity of DNA-damaging chemotherapy.3 Antiinflammatory activity. Decreases cell surface expression of TNFalpha receptors in U937 cells.4 Hydroxychloroquine sulfate has been used to treat alopecia successfully5 and is a clinically useful antimalaria agent. Cell permeable and active in vivo.