CUR 61414, CAS [[334998-36-6]]

Catalog Number: FBM-10-1392
Article Name: CUR 61414, CAS [[334998-36-6]]
Biozol Catalog Number: FBM-10-1392
Supplier Catalog Number: 10-1392
Alternative Catalog Number: FBM-10-1392-5MG, FBM-10-1392-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
Hedgehog pathway antagonist
Molecular Weight: 550.71
Purity: 98% by TLC, NMR (Conforms)
Form: Tan solid
CAS Number: [334998-36-6]
Formula: C31H42N4O5
Application Notes: Novel Hedgehog signaling pathway inhibitor (IC50=100-200 nM). Selectively binds to Smo but not other GPCRs. Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Cell permeable.