PP2, CAS [[172889-27-9]]

Product Overview

• Article Name: PP2, CAS [[172889-27-9]]
• Biozol Catalog Number: FBM-10-1407
• Supplier Catalog Number: 10-1407
• Alternative Catalog Number: FBM-10-1407-5MG, FBM-10-1407-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-(4-Chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Product Description

Src family kinase inhibitor

Product Properties

• Molecular Weight: 301.78
• Purity: 98% by TLC, NMR (Conforms)
• Form: Off-white solid
• CAS Number: [172889-27-9]
• Formula: C15H16ClN5

Application Notes

• Application Notes: Potent and selective Src family kinase inhibitor. Inhibits Lck(IC50=4 nM), Fyn (IC50=5 nM), Hck (IC50=5 nM). It displays weak inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50> 100 µM) and JAK2 (IC50> 50 µM)1. It is a useful probe for exploring the involvement of Src family kinases in signal transduction pathways2.