Chemical Name: 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
PKD inhibitor
Molecular Weight:
396.88
Purity:
98% by TLC, NMR (Conforms)
Form:
Tan solid
CAS Number:
[638156-11-3]
Formula:
C22H21ClN2O3
Application Notes:
Potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 µM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable.
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