Chemical Name: 3-[3-(2-Carboxy-vinyl)-phenyl]-acrylic acid. Alternate Names: 3,3-(1,3-Phenylene)bis(2-propenoic acid)
Aquaporin 1 inhibitor
Molecular Weight:
218.21
Purity:
97% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[37710-81-9]
Formula:
C12H10O4
Application Notes:
Aquaporin-1 inhibitor (IC50 = 8.1 µM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay1.
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