Chemical Name: 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide. Alternate Names: Teriflunomide
DHODH inhibitor
Molecular Weight:
270.21
Purity:
98% by TLC, NMR (conforms)
Form:
White solid
CAS Number:
[108605-62-5]
Formula:
C12H9F3N2O2
Application Notes:
A pyrimidine biosynthesis inhibitor and immunomodulator.1 Inhibits the mitochondrial dihydroorotate dehydrogenase (DHODH).2 Leflunomide is rapidly metabolized in human hepatocytes to A77 1726.3 Cell permeable.
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