Chemical Name: N-Phenylpyridine-4-carbohydrazide. Alternate Names: 4-Pyridinecarboxylic acid 2-phenylhydrazide
Stearoyl CoA desaturase inhibitor
Molecular Weight:
213.24
Purity:
98%
Form:
Beige solid
CAS Number:
[91396-88-2]
Formula:
C12H11N3O
Application Notes:
PluriSln-1 is an inhibitor of stearoyl-coA desaturase (SCD1). PluriSln-1 was able to selectively eliminate human pluripotent stem cells (hPSCs) while not affecting a large array of progenitor and differentiated cells.1 The ability to eliminate potentially tumorigenic undifferentiated cells is important for increasing the safety of hPSC-based treatments. PluriSln-1 has been used to successfully eliminate tumorigenic cells in cardiomyocytes2 and chondrogenic cells3.
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