Chemical Name: N-(3-(Dimethylamino)propyl)-4-(8-hydroxyquinolin-6-yl)benzamide hydrochloride
JMJD2 inhibitor
Molecular Weight:
385.90
Purity:
98% by TLC, NMR (Conforms)
Form:
Olive solid
CAS Number:
[1222800-79-4]
Formula:
C21H23N3O2 HCl
Application Notes:
Inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 µM) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons1.
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