Chemical Name: 5-(Tetradecyloxy)-2-furoic acid. Alternate Names: RMI-14514
Ac-CoA carboxylase inhibitor
Molecular Weight:
324.47
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[54857-86-2]
Formula:
C19 H32 O4
Application Notes:
Interferes with fatty acid synthase via inhibition of acetyl Co-A carboxylase (ACC1)1. Induces apoptosis in a variety of tumor cell lines2,3. Stimulates neurite outgrowth and neuronal differentiation in rat pheochromocytoma cells4. Impairs glucose-stimulated insulin secretion after chronic treatment5.
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