LH-846, CAS [[639052-78-1]]

Product Overview

• Article Name: LH-846, CAS [[639052-78-1]]
• Biozol Catalog Number: FBM-10-1465
• Supplier Catalog Number: 10-1465
• Alternative Catalog Number: FBM-10-1465-5MG, FBM-10-1465-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneaceramide

Product Description

Casein kinase 1delta inhibitor

Product Properties

• Molecular Weight: 316.81
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [639052-78-1]
• Formula: C16H13ClN2OS

Application Notes

• Application Notes: Potent and selective inhibitor of casein kinase (CK) 1delta., IC50s=0.29, 1.3 and 2.5 µM for delta, epsilon and alpha isoforms respectively with no inhibition of CK2. Inhibits CK1delta-mediated phosphorylation and degradation of PER1 protein and lengthens circadian period in U2OS cells.1