Chemical Name: 4-Chloro-N-(6-chloro-3-pyridinyl)benzamide
Kv7.2/7.3 activator
Molecular Weight:
267.12
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[325457-99-6]
Formula:
C12H8Cl2N2O
Application Notes:
A KCNQ2/Q3 (Kv7.2/7.3) activator, EC50=0.38 M (KCNQ1 IC50=15M)1. KCNQ3/Q5 heterodimers are not affected2. Potently dampens neuronal excitability and displays anticonvulsant activity in vivo2.
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