Chemical Name: 2-Amino-6-chloro-alpha-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
AKT activator
Molecular Weight:
364.79
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[305834-79-1]
Formula:
C17H17ClN2O5
Application Notes:
Akt activator. Binds to the pleckstrin homology domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.1 A useful tool for studying the PI3K/Akt axis.2
* VAT and and shipping costs not included. Errors and price changes excepted