Chemical Name: 2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quainazolinone
Adenylate cyclase inhibitor
Molecular Weight:
229.24
Purity:
98% by TLC, NMR (conforms)
Form:
Gold-colored solid
CAS Number:
[299442-43-6]
Formula:
C12H11N3O2
Application Notes:
Potent and selective adenylyl cyclase inhibitor. Selective for AC5 and over AC3 and AC2 (IC50 = 8.3 µM, 132 µM and 1.7 mM respectively)1,2. More recently shown to indiscriminantly inhibit AC63. An extremely useful tool for probing the involvement of adenylyl cylases in cellular signaling4.
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