Chemical Name: 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinzolinone
BET bromodomain inhibitor
Molecular Weight:
370.41
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[1044870-39-4]
Formula:
C20H22N2O5
Application Notes:
RVX-208 is a potent BET bromodomain antagonist with IC50 of 0.510 µM for BD2, with approximately 170-fold selectivity over BD11,2. Increases apolipoprotein A-1 and HDL cholesterol in vitro and in vivo3. Reduces atherosclerosis4.
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