Chemical Name: N,N-(Sulfonyldi-4,1-phenylene)bis(2-chloroacetamide)
Arginine methyl transferase 1 (PRMT1) inhibitor
Molecular Weight:
401.26
Purity:
98% by HPLC NMR (Conforms)
Form:
Brown solid
CAS Number:
[17328-16-4]
Formula:
C16H14Cl2N2O4S
Application Notes:
Selective protein arginine methyltransferase 1 (PRMT1) inhibitor, IC50 = 1.5 µM. Displays no activity against CARM1 and Set7/9 methyltransferases. Inhibits growth of MCF7a breast cancer cells and LNCaP prostate cancer cells. Blocks androgen-induced gene expression in LNCaP cells1.
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