DZNep, CAS [[120964-45-6]]

Product Overview

• Article Name: DZNep, CAS [[120964-45-6]]
• Biozol Catalog Number: FBM-10-1524
• Supplier Catalog Number: 10-1524
• Alternative Catalog Number: FBM-10-1524-1MG,FBM-10-1524-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: 3-Deazaneplanocin A, HCl, NSC 617989

Product Description

Methyl transferase inhibitor

Product Properties

• Molecular Weight: 298.73
• Purity: 98% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [120964-45-6]
• Formula: C12H14N4O3 HCl

Application Notes

• Application Notes: Potent histone methyltransferase inhibitor which decreases global histone methylation1. Inhibits trimethylation of H3K27 and H4K20 in vitro1. Selectively induces apoptosis in multiple cancer cell lines with no effect on normal cells2. May be used in cocktails to chemically induce pluripotent stem cells (CiPSCs) from somatic cells3. Enhances angiogenesis in a mouse model of limb ischemia4.