Chemical Name: N-(3-Cyano-4,5,6,7-tetrahydrobenzo[b]thien-2-yl)-1-naphthalenecarboxamide. Alternate Names: TCS JNK 5a
JNK inhibitor
Molecular Weight:
332.42
Purity:
98% by TLC NMR (Conforms)
Form:
Off-white soilid
CAS Number:
[312917-14-9]
Formula:
C20H16N2OS
Application Notes:
Inhibits JNK2 and JNK3 via binding to the ATP binding domain. Displays little or no activity against JNK1, p38 and a panel of 30 other kinases.1 Induces prometaphase arrest-dependent apoptotic cell death in human Jurkat T cells.2
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