GAC Inhibitor 968, CAS [[311795-38-7]]

Product Overview

• Article Name: GAC Inhibitor 968, CAS [[311795-38-7]]
• Biozol Catalog Number: FBM-10-1538
• Supplier Catalog Number: 10-1538
• Alternative Catalog Number: FBM-10-1538-5MG, FBM-10-1538-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-(3-bromo-4-(dimethylamino)phenyl)-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a]-phenanthridin-4(1H)-

Product Description

Glutaminase C inhibitor

Product Properties

• Molecular Weight: 475.42
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [311795-38-7]
• Formula: C27H27BrN2O

Application Notes

• Application Notes: Allosteric inhibitor of glutaminase C (GAC).1 Inhibition of GAC blocks oncogenic transformation induced by Rho GTPases in fibroblasts and B lymphoma cells with no effect on normal cells.2 Inhibits liver-type glutaminase GLS2 and suppresses breast tumor growth in vivo.3,4 Reverses acquired erlotinib resistance in non-small cell lung cancer.5