Chemical Name: N-1,3,4-thiadiazol-2-yl-3-pyridinecarboxamide
Aquaporin 4 blocker
Molecular Weight:
206.22
Purity:
98% by TLC, NMR (Conforms)
Form:
Off-white solid
CAS Number:
[51987-99-6]
Formula:
C8H6N4OS
Application Notes:
Aquaporin 4 channel blocker, IC50 = 3.1 µM.1 Reduces ischemic cerebral edema in a mouse model of focal cerebral ischemia using MRI.2 Increases regional cerebral blood flow as determined in wild-type and AQP-4 knockout mice.3 Reduces brain edema when administered after onset of ischemia in rat models.4
* VAT and and shipping costs not included. Errors and price changes excepted