Estrogen-related receptor ERRbeta and ERRgamma agonist
Molecular Weight:
311.38
Purity:
98% by TLC NMR (Conforms)
Form:
Yellow solid
CAS Number:
[95167-41-2]
Formula:
C18H21N3O2
Application Notes:
Selective agonist at estrogen-related receptors ERR and ERR with minimal activity at ERR, ER and ER at concentrations up to 30 µM.1 Displays antiproliferative activity in prostate cancer cells.2 Promotes hormone production and cell fusion in cytotrophoblasts.3 In breast cancer cells DY131 arrests cells in G2/M and causes mitotic spindle defects.4 Inhibits osteoclastogenesis and protects against inflammatory bone loss induced by LPS in vivo.5
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