Ro 31-8425 HCl, CAS [[145317-11-9]]

Product Overview

• Article Name: Ro 31-8425 HCl, CAS [[145317-11-9]]
• Biozol Catalog Number: FBM-10-1563
• Supplier Catalog Number: 10-1563
• Alternative Catalog Number: FBM-10-1563-1MG,FBM-10-1563-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: BIM X, Bisindolylmaleimide X

Product Description

PKC inhibitor

Product Properties

• Molecular Weight: 460.96
• Purity: 98% by TLC, NMR (Conforms)
• Form: Red solid
• CAS Number: [145317-11-9]
• Formula: C26H24N4O2 HCl

Application Notes

• Application Notes: Selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCalpha, beta1, beta2, gamma and epsilon, IC50= 8, 8, 14,13 and 39 nM respectively.1 Extremely useful tool for probing PKC-dependent physiology2 or signaling pathways3. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner.4 Cell permeable.