Compound 115-7c, CAS [[908074-72-6]]

Product Overview

• Article Name: Compound 115-7c, CAS [[908074-72-6]]
• Biozol Catalog Number: FBM-10-1567
• Supplier Catalog Number: 10-1567
• Alternative Catalog Number: FBM-10-1567-5MG, FBM-10-1567-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-(5-((Benzyloxycarbonyl)-4-(2,4-dichlorophenyl)-6-methyl-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)butanoic acid. Alternate Names: SW02

Product Description

HSP70 modulator

Product Properties

• Molecular Weight: 477.34
• Purity: 98% by TLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [908074-72-6]
• Formula: C23H22Cl2N2O5

Application Notes

• Application Notes: Acts as an artificial co-chaperone for HSP701. The activity of compound 115-7c mirrors those of HSP40 stimulating the ATPase and protein-folding activities of prokaryotic HSP70. Increases tau levels in cell lines overexpressing tau2. Induces solubilization of polyglutamine and exacerbates polyQ-mediated toxicity3,4. An important probe for understanding HSP70 functions4