Batimastat, CAS [[130370-60-4]]

Catalog Number: FBM-10-1589
Article Name: Batimastat, CAS [[130370-60-4]]
Biozol Catalog Number: FBM-10-1589
Supplier Catalog Number: 10-1589
Alternative Catalog Number: FBM-10-1589-1MG, FBM-10-1589-5MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(methylamine)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butanediamide. Alternate Names: BB-94
Matrix metalloprotease inhibitor (pan-spec.)
Molecular Weight: 477.64
Purity: 98% by HPLC, NMR (Conforms)
Form: White solid
CAS Number: [130370-60-4]
Formula: C23H31N3O4S2
Application Notes: Potent, broad spectrum MMP inhibitor (IC50 =3, 4, 4, 6 and 20 nM for MMPs -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human colon1, ovarian2 and prostate3 xenografts in vivo. Attenuates neuroinflam-mation following focal cerebral ischemia in mice.4 Inhibits alpha-secretase.5 Inhibits snake venom (Bothrops asper) lethality.6