CaCCinh-A01, CAS [[407587-33-1]]

Product Overview

• Article Name: CaCCinh-A01, CAS [[407587-33-1]]
• Biozol Catalog Number: FBM-10-1600
• Supplier Catalog Number: 10-1600
• Alternative Catalog Number: FBM-10-1600-5MG,FBM-10-1600-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

TMEM16A channel blocker

Product Properties

• Molecular Weight: 347.43
• Purity: >98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [407587-33-1]
• Formula: C18H21NO4S

Application Notes

• Application Notes: CaCCInh-A01 is a potent inhibitor of TMEM16A (IC50 = 2.1 mM), a calcium-activated chloride channel1. Blockade of TMEM16A with CaCCInh-A01 protects against renal fibrosis2, reduces blood brain barrier permeability, attenuates brain infarct size and neurological deficits after ischemic stroke3, and induces apoptosis and cell cycle arrest in various epithelium-originated cancer cells4.