Ro 31-6045, CAS [[113963-68-1]]

Product Overview

• Article Name: Ro 31-6045, CAS [[113963-68-1]]
• Biozol Catalog Number: FBM-10-1603
• Supplier Catalog Number: 10-1603
• Alternative Catalog Number: FBM-10-1603-1MG,FBM-10-1603-5MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Bisindolylmaleimide V, BIM V

Product Description

p70 S6 Kinase inhibitor

Product Properties

• Molecular Weight: 341.36
• Purity: 98% by TLC, NMR (Conforms)
• Form: Orange solid
• CAS Number: [113963-68-1]
• Formula: C21H15N3O2

Application Notes

• Application Notes: This bis indolylmaleimide derivative is a potent inhibitor of the mitogen-stimulated protein kinase p70 (S6K) acting independently of its upstream activator mTOR.1 Does not inhibit PKC (at concentrations <100 µM) and therefore may be used as a negative control for bisindolylmaleimide PKC inhibitors2 such as GF 109203X3 and other structurally related inhibitors4.