Chemical Name: 5-(1-Piperazinylsulfonyl)isoquinoline dihydrochloride
Multi-kinase inhibitor
Molecular Weight:
350.26
Purity:
98% by HPLC, NMR (Conforms)
Form:
White to off-white solid
CAS Number:
[84468-24-6]
Formula:
C13H15N3O2S2HCl
Application Notes:
Inhibits the following kinases PKG (IC50=4 mM), PKA (IC50=8 mM), PKC (IC50=12 mM).1 Increases human fibroblast reprogramming efficiency with PD0325901, CHIR99021, A83-01 and hLIF.2 Improves single cell survival and supports high cloning efficiency in human pluripotent stem cells.3
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