Chemical Name: 1-Isoquinolin-6-yl-3-(2-oxo-2-pyrrolidin-1-yl-ethyl)-urea
PRMT3 inhibitor
Molecular Weight:
298.34
Purity:
98% by TLC, NMR (Conforms)
Form:
Beige solid
CAS Number:
[1687736-54-4]
Formula:
C16H18N4O2
Application Notes:
Potent and selective allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).1 IC50 = 31 nM and selective against 31 other methyltransferases. An extremely useful probe for investigating the role of PRMT3 in normal and pathophysiology. Cell permeable and active in vivo.
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