Chemical Name: 2(S)-(2-Oxopyrrolidin-1-yl)butyramide
Anticonvulsant
Molecular Weight:
170.21
Purity:
98% by HPLC NMR (conforms)
Form:
White solid
CAS Number:
[102767-28-2]
Formula:
C29H14N2O2
Application Notes:
Levetiracetam is a clinically useful non-classical anticonvulsant.1 It has no effect on voltage-dependent Na+ channels, GABAergic transmission, or affinity for either GABAergic or glutaminergic receptors.2,3 Levetiracetam is believed to act via binding to the synaptic vesicle protein SV2A.4 Levetiracetam reduced intra-neuronal Ca2+ levels by inhibition of ryanodine and IP3 receptor-dependent Ca2+ release from the endoplasmic reticulum.5 It was also observed to lower the pH of neocortical pyramidal cells via weakening of the transmembrane HCO3(-)-mediated acid-extrusion.6
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