Actinomycin D, CAS [[50-76-0]]

Product Overview

• Article Name: Actinomycin D, CAS [[50-76-0]]
• Biozol Catalog Number: FBM-10-2054
• Supplier Catalog Number: 10-2054
• Alternative Catalog Number: FBM-10-2054-5MG,FBM-10-2054-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Transcription inhibitor

Product Properties

• Molecular Weight: 1255.42
• Purity: >98% by HPLC NMR (conforms)
• Form: Orange-red solid
• CAS Number: [50-76-0]
• Formula: C62H86N12O16

Application Notes

• Application Notes: Actinomycin D (50-76-0) is a cyclopeptide antibiotic and intercalating transcription inhibitor with anti-neoplastic activity. Potent inhibitor of RNA polymerase.1 Induces apoptosis in a variety of cancer cell lines2,3via the intrinsic pathway4. Upregulates proapoptotic PUMA and downregulates Bcl-2 mRNA in peripheral blood lymphocytes.5