Chemical Name: Fermentation product from Streptomyces hygroscopicus. Alternate Names: FK-520, FR-900520
FKBP ligand, immunosuppressant
Molecular Weight:
729.03
Purity:
99% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[11011-38-4]
Formula:
C43H69NO12
Application Notes:
Analog of FK-506. Potent immunosuppressant1. Binds to FKBP122 and inhibits calcineurin and NFAT. Displays antiinflammatory effects in skin diseases3. Cell permeable and active in vivo.
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