Chemical Name: 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexanoic acid. Alternate Names: NSC129185
Immunosuppressant
Molecular Weight:
320.35
Purity:
98% by TLC, NMR (Conforms)
Form:
White solid
CAS Number:
[24280-93-1]
Formula:
C17H20O6
Application Notes:
Immunomodulator1. Blocks the biosynthesis of guanine nucleotides via inhibition of inosine 5-monophosphate dehydrogenase which suppresses the production of proinflammatory cytokines, nitric oxide and LDH in macrophages2,3. Inhibits IL-2 -dependent T cell proliferation4.
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