Chemical Name: N-(2-Pyrazine)carbonyl-L-phenylalanine-L-leucine boronic acid. Alternate Names: MG-341, PS-341, MLN341
Proteasome inhibitor
Molecular Weight:
384.25
Purity:
98% by TLC, NMR (conforms)
Form:
White solid
CAS Number:
[179324-69-7]
Formula:
C19H25BN4O4
Application Notes:
Potent and selective proteasome inhibitor (Ki=0.6 nM). Inhibits proliferation of a number of tumor cell lines (IC50=7 nM). Inhibits TNF synthesis and FGF-induced angiogenesis. Reversible. Cell permeable.
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