Chemical Name: 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide. Alternate Names: SC-58635
COX II inhibitor
Molecular Weight:
381.38
Purity:
99% by HPLC NMR (Conforms)
Form:
White solid
CAS Number:
[169590-42-5]
Formula:
C17H14F3N3O2S
Application Notes:
Selective inhibitor of cyclooxygenase-2 (COX-2) IC50 = 15 and 0.04 mM for COX-1 and COX-2 respectively1. Potent and clinically useful antiinflammatory agent2. Cancer chemopreventive agent3. May act synergistically with currently used anticancer agents4. Cell permeable, active in vivo.
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