Lenalidomide, CAS [[191732-72-6]]

Product Overview

• Article Name: Lenalidomide, CAS [[191732-72-6]]
• Biozol Catalog Number: FBM-10-2148
• Supplier Catalog Number: 10-2148
• Alternative Catalog Number: FBM-10-2148-100MG, FBM-10-2148-500MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (R,S)-3-(4-Amino-1-oxo-3H-isoindol-2-yl)piperidine-2,6-dione. Alternate Names: CC-5013

Product Description

Immunomodulator

Product Properties

• Molecular Weight: 259.26
• Purity: 98% by TLC, NMR (Conforms)
• Form: White solid
• CAS Number: [191732-72-6]
• Formula: C13H13N3O3

Application Notes

• Application Notes: Thalidomide analog which, like thalidomide,1 binds to cereblon which is the substrate recognition component of a cullin-dependent ubiquitin ligase and inhibits its autoubiquitination activity2. Induces degradation of T-cell repressors Ikaros (IKZF1) and Aiolos (IKZF3) leading to T cell activation2. Selective inhibition of IKZF1 and IKZF3 in multiple myeloma cells results in cell death3,4. Cell permeable. Caution: Teratogenic