Potent and selective FLT3 inhibitor (IC50= 2 nM)1,2. Inhibits RET and RET phosphorylation in medullary thyroid carcinoma cells3. Suppresses JAK2/STAT5 signaling and the proliferation of primary erythroid cells from patients with myeloproliferative disorders4. Potent Trk inhibitor5. Cell permeable.
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